Elevated airway liquid volumes at birth: a potential cause of transient tachypnea of the newborn

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Transient Tachypnea of the Newborn

Transient tachypnea of the newborn (TTN) is a disease common in infants throughout the world and has been encountered by all physicians who care for newborn infants. Infants with TNN present within the first few hours of birth with tachypnea, increased oxygen requirement, and occasional hypoxia noted on arterial blood gases without concomitant carbon dioxide retention. When managing an infant w...

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Transient tachypnea of the newborn.

product/device. Introduction The birth of a child is preceded by several changes to prepare for the transition from intrauterine to extrauterine life. The five major events that establish the lungs as the organ of gas exchange at birth include: clearance of fetal lung fluid, establishment of spontaneous breathing, decrease in pulmonary vascular resistance, release of surfactant, and cessation o...

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Effects of Salbutamol on the Treatment of Transient Tachypnea of the Newborn

Background: This study aimed to evaluate the safety and efficacy of inhaled salbutamol for the treatment of Transient Tachypnea of the Newborn (TTN). Methods: Totally, 80 neonates with TTN were randomly assigned into two groups of treatment and placebo. The treatment and placebo groups received one dose of nebulized salbutamol (dose of 0.15 ml/kg in 2 ml of normal saline) and only 2 ml 0.9% no...

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Transient tachypnea of the newborn: Is empiric antimicrobial therapy needed?

BACKGROUND Transient tachypnea of the newborn (TTN) is a self- limited increase in the work of breathing in near- and full-term infants; it is attributed to a delay in the clearance of alveolar fluids. Prophylactic antibiotics are usually administered until blood cultures are reported negative for 48 hours. OBJECTIVES To prospectively compare outcomes of infants presented with classic TTN who...

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Surfactant deficiency in transient tachypnea of the newborn.

OBJECTIVE To evaluate surfactant production and function in term neonates with transient tachypnea of the newborn (TTN). STUDY DESIGN Samples of gastric aspirates collected within 30 minutes of birth from 42 term newborns with gestational age ≥ 37 weeks (21 patients with TTN and 21 control subjects), delivered via elective cesarean delivery, were analyzed with lamellar body count and stable m...

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ژورنال

عنوان ژورنال: Journal of Applied Physiology

سال: 2017

ISSN: 8750-7587,1522-1601

DOI: 10.1152/japplphysiol.00464.2017